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Chronic pyelonephritis
Chronic pyelonephritis
A chronic tubulointerstial renal disorder characterized by renal inflammation and fibrosis induced by recurrent or persistent renal infection, vesicoureteral reflux or urinary tract obstruction.
Gross:
Gross:
Irregular coarse, corticomedullary scars usually at poles, overlying dilated, blunted or deformed calyces.
Dilated ureter; retraction and destruction of papillae with "U” shaped scar
Microscopy
Microscopy
Chronic pyelonephritis (1).png
Renal parenchyma with lymphocytic infiltration and fibroblastic proliferation in the interstitium.
Thyroidisation of tubules with periglomerular fibrosis.
Diagnosis
Diagnosis
Chronic pyelonephritis
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