A. Intestinal Tuberculosis

Intestines: 

The lesions include infections, inflammatory conditions and neoplastic lesions.

Intestinal Tuberculosis:

Primary- caused by M.tuberculosis Bovis and transmitted by ingestion of infected foods /drinking unpasteurized milk from TB infected cows. 

Secondary -results in advanced open pulmonary disease wherein the discharge from lung lesions are subsequently swallowed.

Common sites – ileocaecal junction and anal region 

History: 

38year-old female presented with evening raise to temperature for past 2 months and pain abdomen. 

Key Questions & Answers

1) Describe the gross features of the specimen.

1. Specimen of intestine with mucosa showing transverse ulcer.

2. Thickening of wall seen..

2) Identify the microscopic features of the given slide.

1. Section of intestine with  granulomatous inflammation in the submucosa.

2. Granuloma is composed of caseous necrosis, epithelioid cells, langhans giant cells and lymphocytes.

3) Diagnose the pathological condition correlating the history, gross and microscopic features. 

Intestinal tuberculosis.

4) What are the complications of the above lesion. 

Stricture, Adhesions, Perforation.

5) What are the common causes of intestinal ulcers.

Tubercular ulcer, Amebic ulcer and thyphoid ulcer.