B. Myocardial Infarction

Refers to death of cardiac muscle due to prolonged sever ischemia.

The risk factors include high blood pressure, smoking, diabetes, lack of exercise, obesity and hypercholesterimia.

The underlying mechanism is generally complete blockage of coronary artery caused by rupture of an atherosclerotic plaque or a coronary artery spasm.

Gross:

The infarcted area appears pale tan to pale gray, often sharply demarcated from the normal color of adjacent viable tissue
It appears solid and firm

Microscopy

Myocardial Infarction (1).png

1. Coagulative necrosis of cardiac fibers displaying retained cellular outlines (architecture), increased eosinophilia of the cytoplasm and loss of nuclei.

2. Neutrophilic infiltration seen between the necrosed cells and normal myocardial fibers

Diagnosis

Myocardial Infarction

Key Questions & Answers

1.What is the type of necrosis seen in the myocardial infarction.

Ans: Coagulative necrosis.

2.Mention the complications of myocardial infarction.

Ans: Transmural infarction.

Arrhythemias
Mural thrombus & embolism
Rupture
Anerysm
Cardiac tamponade
Pericarditis
Cardiobenic shock

B) Subendocardial MI

Mural thrombosis
Pericarditis
Aneurysm
Rupture

Page updated

Google Sites

Report abuse