C. Chondrosarcoma

C. Chondrosarcoma: 

A cartilage forming tumor often seen to involve the flat bones and central skeleton in elderly males. Radiologically the low grade component manifests as mineralized areas with rings and arcs while the high grade component appears lytic and aggressive, with permeation and destruction of underlying bone. 

History:

52-year-old male patient presented with a painful swelling in the left pelvis. 

Key Questions & Answers

1.Describe the gross features of the specimen

   a.Specimen of ribs

   b.Grey white tumor with mucoid areas

2.Identify the microscopic features of the given slide

   a.Atypical chondrocytes arranged in sheets and lobules in a hyaline matrix

   b.Tumor cells show pleomorphism and nuclear atypia

3.Diagnose the pathological condition correlating the history, gross and microscopic features

    Chondrosarcoma 

4.Write common sites of involvement of the above lesion

   Central skeleton – pelvis, ribs, shoulder

5.Mention the common age group involved

   40-60 years