Is one of the most common visceral malignancies in male arising from the epithelium of the bronchus or bronchiole. While smoking is a major risk factor, industrial hazards, and atmospheric pollutants also play a role.
1. Specimen of lung
2. Cut section shows nodular tumor arising from the bronchus obliterating its lumen
Pleomorphic polyhedral tumor cells with hyperchromatic nuclei, abundant cytoplasm seen in sheets and clusters
Keratin pearl seen
Alveoli, anthracotic pigment and bronchial cartilage seen
Bronchogenic carcinoma
1. What are gross features of the specimen?
Ans: Cut section of a specimen of a lung showing grey white mass obstructing the lumen of the bronchus.
2.What is the most important associated carcinogen of this condition ?
Ans: Cigarette smoke
3. Write the microscopic features.
Ans: Malignant squamous cells in sheets and singles.
Keratin pearls present.
4.Name the main types of bronchogenic carcinoma.
Ans:i. Squamous cell carcinoma.
ii. Adenocarcinoma.
iii. Small cell carcinoma.
iv. Large cell carcinoma.
5.Which type of lung carcinoma has a bad prognosis?
Ans: Small cell carcinoma.