A. Lipoma

A. Lipoma:

These are benign tumors of adipose tissue. They could be single or multiple, are usually subcutaneous and the common sites include the upper back, shoulders, neck and extremities. 

The cause is generally not clear but there is an increased association with family history, obesity, and lack of exercise.

They are soft, mobile, non tender and treatment is surgical excision.

History: 

30 year-old male patient presented with swelling in the nape of the neck. 

Key Questions & Answers 

1) Describe the gross features of the specimen.

1. Well encapsulated lesion

2. C/S yellowish color and shows a lobular architecture

2) Mention the microscopic features of the given slide.

1. Proliferation of mature adipocytes in sheets and lobules separated by fibrous septa containing blood vessels.

2. Adipocytes are round to oval with clear cytoplasm and peripheral nuclei.

3) Diagnose the pathological condition correlating the history, gross and microscopic features.

Lipoma

4) What is the special technique and special stains used to demonstrate the accumulated material?

1. Special technique – Frozen section

2. Special stains – Sudan black, Oil Red O, Sudan 3, Sudan 4

5) What is the malignant counterpart of this lesion? 

Liposarcoma