i. Tuberculoid Leprosy

Tuberculoid Leprosy

Results when the host mounts T-cell mediated immune response

Gross:

Begins with localized skin lesions which enlarge and develop irregular shape with indurated hyper pigmented margins and depressed pale centre.

Microscopy:

Tuberculoid Leprosy (1).png

1. Non caseating granulomas seen in the dermis, Langhan’s giant cells may be seen

2. Skin with normal epidermis, no clear zone seen

3. Fite Faraco: the special stain for Mycobacterium leprae, show no bacilli

Diagnosis

Tuberculoid Leprosy

Key Questions & Answers

1.Name the causative organism

The causative organism is Mycobacterium leprae

2.Mention causes for granulomatous inflammation

The following are some of the causes of granulomatous inflammation: Tuberculosis, Leprosy, Syphilis, Cat scratch disease, Sarcoidosis, Schistosomiasis, Deep fungal infections and Reactions to foreign body

3.Classify leprosy

Leprosy is chiefly classified as Tuberculoid leprosy and Lepromatous leprosy

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