Chart-14

15 year old boy with swollen knee joints presented with prolonged bleeding following tooth extraction

LABORATORY FINDINGS

Hemoglobin:                         9 gm/dl

Total leucocyte count:        6900 cells/cmm 

Platelet count:           1.9lakhs/cmm 

Bleeding time :                         3 mins 

Clotting time :                         12 mins 

APTT:                                        55 secs 

 A. Interpret the above findings and give your diagnosis. 

 A young boy with swollen knee joints (hemarthrosis), delayed bleeding following tooth extraction, prolonged clotting time and prolonged partial thromboplastin time 

Diagnosis: Coagulation disorder 

B. Mention two inherited and two acquired coagulation disorders 

1. Inherited coagulation disorders 

• Hemophilia A (Factor VIII deficiency) 

• Hemophilia B (Factor IX deficiency) 

• Von-Williebrand disease 

• Hypofibrinogenemia 

2. Acquired coagulation disorders 

• Deficiency of Vitamin K dependent factors 

• Disseminated Intravascular Coagulation 

• Chronic liver disease