Chart-1

70 year old male with h/o malena.

On examination- severe pallor

Laboratory Findings

Histogram

PERIPHERAL BLOOD SMEAR 

A.Interpret the histogram and peripheral blood smear. 

• Hb- 9.7 gm/dl ↓ 

• RBC- 4.28 mil/cumm ↓ PCV- 29.9 % ↓ 

• MCV- 69.7 fl ↓ 

• MCH- 22.6 pg ↓ 

• MCHC- 30.4 gm % ↓ 

• RDW- 18.4 % ↑ 

Histogram 

• shift to left indicates microcytosis 

• broad base indicates anisocytosis 

Peripheral blood smear 

• RBC s are microcytic and hypochromic, elliptocytes seen 

• WBC s are normal in number, morphology and distribution 

• Platelets adequate 

B. What is your diagnosis? 

Microcytic hypochromic Anemia 

C. What is the probable cause? 

Iron deficiency Anemia 

D. What are the biochemical findings in the above case? 

• Serum Iron- low (50 to 150 μg/dl) 

• Serum Ferritin- low (N- 15 to 300 μg/dl) 

• Transferrin saturation- low (N-16 to 50%) 

• TIBC- increased (N-300-360 μg/dl)